THROUGH LINES
How a Limited Women's Health Definition Inadequately Shapes Research, Investment and Care Delivery
Women’s health is structurally underserved across research, care access and outcomes – and the cost of inaction is measurable in both lives and economic terms.
Key Takeaways
- Sexual and reproductive health accounts for just 5% of women's total health burden, yet this limited framing continues to drive research funding, clinical training and benefit design – leaving the estimated 56% of burden from conditions that disproportionately affect women, including cardiovascular disease, autoimmune disorders and mental health, underdiagnosed and undertreated.
- Women represent more than 50% of the population but account for only 42% of clinical trial participants – a gap that widens by disease state, with women comprising just 37% of cardiovascular and 40% of kidney disease study participants despite bearing 51% and 57% of those conditions' global disease burden, respectively.
- Maternal mortality has risen 131.9% since 1987 – reaching 16.7 deaths per 100,000 live births in 2025 and more than 3x the average of peer OECD nations – even as 59% of rural hospitals no longer offer labor and delivery services and a shortage of 9,260 OB-GYNs is projected by 2038.
Report Summary
Despite decades of clinical investment and policy focus, women’s health in the U.S. remains structurally underserved and strategically underprioritized. Moreover, growing demand and a recent increase in investment activity have not translated into better outcomes.
Women are faced with fragmented benefit design, gaps in access to care and health outcomes that lag peer countries. These disparities are most evident in the ongoing maternal health crisis, characterized by a maternal mortality rate that has risen 131.9% since 1987 and is now more than 3x the average of other high-income OECD countries – despite the fact that an estimated 84% of pregnancy-related deaths in the U.S. are preventable.1,2,3
Although women are the primary healthcare decision-makers within households, existing care models, reimbursement structures and clinical research do not appropriately prioritize their needs. The scope of women’s health is often limited to sexual and reproductive care, which only accounts for 5% of women’s total health burden even though an estimated 56% of that burden stems from conditions that disproportionately affect or manifest differently in women, including autoimmune diseases, cardiovascular disease and mental health disorders.4
This misalignment between perception and reality manifests in suboptimal resource allocation – how research is funded, clinicians are trained and benefits are designed – that compounds over time. The historic misallocation of resources is amplified by emerging technologies, evolving reproductive patterns and widening access gaps, which compels a reevaluation of how, where and for whom women’s healthcare is delivered.
This analysis examines seven critical trends that are reshaping women’s health access, delivery and investment:
- The narrow definition of women’s health deemphasizes underdiagnosed and undertreated conditions.
- Female underrepresentation in clinical research contributes to adverse outcomes and limits clinical efficacy.
- Fertility trends and rising use of assisted reproductive technology (ART) are reshaping reproductive demand for fertility care and reproductive autonomy.
- Maternal mortality is increasing as access to obstetric care is decreasing – particularly among racial minorities.
- Midlife and post-reproductive care remain underprioritized.
- Declining physician supply and labor and delivery closures are narrowing the availability of women’s healthcare.
- Commercialization and consumerization of care are reshaping access and incentives through direct-to-consumer platforms and private equity deals.
Together, these trends are disrupting where women seek care, which providers deliver it and how costs and utilization are distributed across the lifespan.
Women’s healthcare spans every life stage, accounting for a disproportionate share of aggregate care utilization – making it a core driver of system performance, rather than a discrete service line. Stakeholders who continue to treat it as such risk misaligned capital investment, workforce planning, benefit design and care models required to manage this complex population effectively. Successful health system performance will depend in large part on how well it provides comprehensive care for women.
Methodology
To conduct this analysis, secondary data were obtained from a variety of publicly available resources, including reports from the U.S. Department of Health and Human Services (including Centers for Disease Control Prevention, National Center for Health Statistics and Health Resources Services Administration), global health policy and research organizations.
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